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662098  UbcH5c Conjugating Enzyme E2, Human, Recombinant, E. coli

UBD2D3, Ubiquitin-conjugating enzyme E2 D3

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09 February 2012

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662098-50UG  50 μg 
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Full-length, recombinant, human UbcH5c expressed in E. coli. UbcH5c, an E2 ubiquitin ligase, is highly homologous to the yeast UbC4/5 family of E2 enzymes. UbcH5c, together with UbcH5a and UbcH5b, are the most active class of E2 enzymes in cell extracts and are associated with regulation of transcription factors such as p53, NF-κB3, and c-Fos. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
Product information
Formulation In 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.0.
Molar mass 17000
Avoid freeze/thaw Yes
Purity ≥95% by SDS-PAGE
Store and ship information
Storage ≤ -70°C
Ship Dry Ice Only
Standard Handling

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© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.

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