PF039
GDNF, Rat, Recombinant, S. frugiperda
rrGDNF, Glial Derived Neurotrophic Factor
For general questions please contact our Customer Service:
EMD Chemicals, Inc.
480 S. Democrat Road
08027 Gibbstown
United States
Phone: 800 854 3417
Fax: 800 776 0999
E-mail: Customer.CareDesk@emdchemicals.com
09 February 2012
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Recombinant, rat glial derived neurotrophic factor expressed in S. frugiperda insect cells. Native GDNF exists as a disulfide homodimeric glycoprotein and is a novel member of the TGF-β superfamily. Titrate the protein for optimal results in individual systems. Immbolized rrGFRa/Fc at 2 µg/ml (100 µl/neu) can bind GDNF at a linear range of 0.1-10 ng/ml.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Formulation | Lyophilized from 35% Acetonitrile, 0.1% TFA, 50 µg BSA/µg GDNF. | ||
| Avoid freeze/thaw | Yes | ||
| Biological activity | ED50 = 1-3 ng/ml as measured by the ability to support the survival and stimulate neurite outgrowth of cultured embryonic chick dorsal root ganglia. Immbolized rrGFRα/Fc at 2 µg/ml (100 µl/neu) can bind GDNF at a linear range of 0.1-10 ng/ml. | ||
| Purity | ≥97% by SDS-PAGE | ||
| Contaminants | Endotoxin: ≤1 EU/µg GDNF | ||
| Solubility | Sterile PBS containing ≥0.1% HSA or BSA | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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