176880
Anisomycin, Streptomyces griseolus
2-(p-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate
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EMD Chemicals, Inc.
480 S. Democrat Road
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United States
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13 February 2012
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Strongly activates stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase in mammalian cells. Synergizes with growth factors to induce c-fos and c-jun by acting as a potent signaling agonist. An inhibitor of protein synthesis at the translation step. Also known to induce apoptosis in the human monoblastoid cell line, U937.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Molar mass | 265.3 | ||
| Purity | ≥98% by TLC | ||
| Solubility | DMSO or MeOH | ||
| Chemical formula | C14H19NO4 | ||
| RTECS | BZ9800000 | ||
| CAS number | 22862-76-6 | ||
| Merck USA index | 14, 670 | ||
| Store and ship information | |||
|---|---|---|---|
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Toxic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36/37/39-45 Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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| R Phrase |
R: 23/24/25 Toxic by inhalation, in contact with skin and if swallowed. |
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