681671
Wnt Antagonist II, IWP-2
Inhibitor of Wnt Production-2, Wnt Pathway Inhibitor II
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Merck KGaA
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64293 Darmstadt
Germany
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15 Februar 2012
wird geladen
A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/β-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses.
| Produktinformationen | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Protect from Light | Ja | ||
| Packaged under inert gas | Ja | ||
| Purity | ≥95% by HPLC | ||
| Chemische Formel | C22H18N4O2S | ||
| CAS-Nummer | 686770-61-6 | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
| Lagerkategorie | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Sicherheitshinweise | |||
|---|---|---|---|
| S-Satz |
S: 22-24/25-36-45 |
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| R-Satz |
R: 20/21/22 |
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