662087
UCH-L1, His•Tag® , Mouse, Recombinant, E. coli
Ubiquitin C-terminal Hydrolase L1, Ubiquitin thioesterase L1
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Merck KGaA
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64293 Darmstadt
Germany
Teléfono: +49 6151 72-0
Fax: +49 6151 72 2000
15 febrero 2012
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Full-length, recombinant, mouse UCHL-1 fused at the N-terminus to His•Tag® sequence and expressed in E. coli. UCH-L1 is a member of the low molecular weight UCHs that processes ubiquitin precursors and ubiquitinated proteins to generate monomeric ubiquitin. The expression of UCH-L1 is highly specific to cells of the neuroendocrine system and their tumors. UCH-L1 variants (Ile93Met) have been linked to Parkinson disease and may participate in processes critical for neuronal health. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
| Información sobre producto | |||
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| Formulation | In 50 mM HEPES, 2 mM DTT, pH 8.0. | ||
| Avoid freeze/thaw | Si | ||
| Purity | ≥95% by SDS-PAGE | ||
| Almacenar y enviar información | |||
|---|---|---|---|
| Categoría de alamacenamiento | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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