662103
UbcH13 Conjugating Enzyme E2, His•Tag®, Human, Recombinant, E. coli
Ubc13, UBE2N, Ubiquitin-conjugating enzyme E2 N
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
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Full-length, recombinant, human UbcH13 fused at the N-terminus to a His•Tag® sequence and expressed in E. coli. UbcH13, an E2 ubiquitin ligase, forms a heterodimeric complex with Uev1, and is able to assemble K63-linked polyubiquitin chains, which have novel regulatory roles. These ubiquitin chains have a role in a variety of processes such as DNA repair, endocytosis, polysome stability, and signal transduction pathways. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In PBS, 1 mM DTT, 10% glycerol, pH 7.2. | ||
| Molar mass | 42000 | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥95% by SDS-PAGE | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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