662103
UbcH13 Conjugating Enzyme E2, His•Tag®, Human, Recombinant, E. coli
Ubc13, UBE2N, Ubiquitin-conjugating enzyme E2 N
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
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15 Februar 2012
wird geladen
Full-length, recombinant, human UbcH13 fused at the N-terminus to a His•Tag® sequence and expressed in E. coli. UbcH13, an E2 ubiquitin ligase, forms a heterodimeric complex with Uev1, and is able to assemble K63-linked polyubiquitin chains, which have novel regulatory roles. These ubiquitin chains have a role in a variety of processes such as DNA repair, endocytosis, polysome stability, and signal transduction pathways. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
| Produktinformationen | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In PBS, 1 mM DTT, 10% glycerol, pH 7.2. | ||
| Avoid freeze/thaw | Ja | ||
| Purity | ≥95% by SDS-PAGE | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
| Lagerkategorie | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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