For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
loading
Recombinant streptokinase expressed in E. coli. Catalyzes the hydrolysis of amide linkages. Forms a 1:1 complex with plasminogen, which is then converted to streptokinase-plasmin. Both streptokinase-plasminogen and streptokinase-plasmin complexes can activate plasminogen. As a result of its interaction with human or rabbit plasminogen, streptokinase undergoes specific fragmentation.
Note: 1 KU = 1000 units.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized solid | ||
| Formulation | Supplied as 10% protein (enzyme) and 90% stabilizer (HSA). | ||
| Molar mass | 47400 | ||
| Unit definition | One unit is defined as the amount of enzyme that will liquefy a standard clot of fibrinogen, plasminogen, and thrombin in 10 min at 37°C, pH 7.5. | ||
| Activity | ≥5000 units/mg solid | ||
| Purity | ≥95% by SDS-PAGE | ||
| Source | Prepared using HSA from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| pH value | optimum 6.8 - 7.5 | ||
| PI | 5.2 | ||
| Solubility | H2O or Aqueous buffers | ||
| RTECS | OB8880000 | ||
| CAS number | 9002-01-1 | ||
| Merck USA index | 14, 8825 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Blue Ice Only
Harmful |
||
