481400
NF-κB Antisense Oligonucleotide, Sodium Salt
NK-κB AS, 5′-TGGATCATCTTCTGCCATTCT-3′
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
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A 21-meric phosphorothioate oligonucleotide that targets the sequences including and immediately upstream of the initiation codon of NF-κB. Inhibits expression of the chloramphenicol acetyl-transferase (CAT) gene that is under the control of a NF-κB-responsive element in (NF-κB)3CAT, a NF-κB-responsive element. Reported to suppress both the constitutive and the TNFα-induced Keratin K6b promoter activity, which contains NF-κB responsive element.
Note: 50 nmol = 355 µg.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Molar mass | 7099.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥90% by PAGE | ||
| Solubility | H2O | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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