444289
Marimastat
(2S,3R)-N4-((1S)-2,2-Dimethyl-1-((methylamino)carbonyl)propyl)-N¹,2-hydroxy-3-(2-methylpropyl)butanediamide, BB-2516
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
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14 Februar 2012
wird geladen
An orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor (IC50 in nM = 5, 6, 200, 20, 2, 1.8 and 3.8 for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively) that targets both the substrate binding site and the active-site Zn2+. Marimastate is widely used in studying the involvement of MMPs in various cellular and pathological processes both in vitro and in vivo.
| Produktinformationen | |||
|---|---|---|---|
| Form | White solid | ||
| Protect from Light | Ja | ||
| Packaged under inert gas | Ja | ||
| Purity | ≥98% by NMR | ||
| Chemische Formel | C15H29N3O5 | ||
| CAS-Nummer | 154039-60-8 | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
| Lagerkategorie | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
| Sicherheitshinweise | |||
|---|---|---|---|
| S-Satz |
S: 22-24/25-36/37/39 |
||
