420210
Jervine
(3β, 23β)-17,23-Epoxy-3-hydroxyveratraman-11-one, 11-Ketocyclopamine, Shh Signaling Antagonist III
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Merck KGaA
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64293 Darmstadt
Germany
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14 Februar 2012
wird geladen
A cell-permeable steroidal alkaloid similar to cyclopamine (Cat. No. 239803) that displays teratogenic effects and induces cyclopia by blocking shh (Sonic Hedgehog) signaling (IC50 = ~ 500-700 nM in s12 cells). Tomatidine (Cat. No. 614350) serves as a suitable negative control.
| Produktinformationen | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Primary Target | induces cyclopia by blocking shh (Sonic Hedgehog) signaling (IC50 ~ 500-700 nM in s12 cells) | ||
| Packaged under inert gas | Ja | ||
| Purity | ≥98% by HPLC; single spot by TLC | ||
| Chemische Formel | C27H39NO3 | ||
| RTECS | WG9700000 | ||
| CAS-Nummer | 469-59-0 | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Lagerkategorie | -20°C | ||
| Ship |
Shipped with Blue Ice or with Dry Ice
Toxic |
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