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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Fax: +49 6151 72 2000
15 Februar 2012
wird geladen
Unique aminoglycoside antibiotic that inhibits the growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells. Inhibits protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA. Hph, a gene from E. coli, encodes resistance to hygromycin B and can be isolated and cloned by recombinant DNA techniques. This hygromycin B-resistance gene is particularly useful for identification or selection of recombinant clones in a variety of cell types. Hygromycin B penetrates cells that have been permeabilized by virus infection and can act as an effective antiviral agent.
Bioassay: 350-450 units/mg Hygromycin B. 106 units is equivalent to ~900 mg.
Supplied with a directional insert. Note: 1 KU = 1000 units; 1 MU = 1,000,000 units.
| Alternative Produkte für Hygromycin B, Streptomyces sp. | |
| 400052 | Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in PBS, Cell Culture-Tested |
| 400049 | Hygromycin B, Streptomyces sp. |
| 400053 | Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in 25 mM HEPES, Cell Culture-Tested |
| Zubehör fürHygromycin B, Streptomyces sp. |
| Produktinformationen | |||
|---|---|---|---|
| Form | Dark brown liquid | ||
| Primary Target | growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells | ||
| Secondary target | protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA | ||
| Biological activity | The activity of Hygromycin B is measured in a zonal inhibition assay using Bacillus subtilis. The activity is measured relative to a reference standard. | ||
| Purity | >85% by HPLC | ||
| Chemische Formel | C20H37N3O13 | ||
| RTECS | WK2130000 | ||
| CAS-Nummer | 31282-04-9 | ||
| Merck USA index | 14, 4852 | ||
| Lager- und Versandinformationen | |||
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Lagerkategorie | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Highly Toxic & Carcinogenic / Teratogenic |
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| Sicherheitshinweise | |||
|---|---|---|---|
| S-Satz |
S: 23-26-36/37/39-45 |
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| R-Satz |
R: 26/27/28-37/38-41 |
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