382172
Histone Deacetylase Inhibitor VI, HNHA
N-Hydroxy-7-(2-naphthylthio)heptanomide
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15 febrero 2012
cargando
A cell-permeable hydroxyamide-based SAHA analog that potently inhibits histone deacetylase (HDAC) activity (IC50 = 100 nM). Shown to induce histone acetylation and p21 transcription with concomitent inhibition of cell cycle progression in human fibrosarcoma HT1080 cells. Reported to be more potent than SAHA in inhibiting tumor growth in a murine xenograph model in vivo.
| Información sobre producto | |||
|---|---|---|---|
| Form | White solid | ||
| Protect from Light | Si | ||
| Packaged under inert gas | Si | ||
| Purity | ≥95% by HPLC | ||
| Fórmula químico | C17H21NO2S | ||
| Número CAS | 926908-04-5 | ||
| Almacenar y enviar información | |||
|---|---|---|---|
| Categoría de alamacenamiento | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Irritant |
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| Información de seguridad | |||
|---|---|---|---|
| Frase S |
S: 22-24/25-36/37/39 |
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| Frase R |
R: 36/37/38 |
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