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14 February 2012
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A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Activation of histamine H1 receptors leads to Ca2+ mobilization, whereas histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Stimulated time- and concentration-dependent increase in p38 and p42/p44 MAP kinases in DDT(1) MF2 cells.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Molar mass | 111.2 | ||
| Protect from Light | Yes | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥97% by TLC | ||
| Solubility | H2O | ||
| Chemical formula | C5H9N3 | ||
| RTECS | MS1050000 | ||
| CAS number | 51-45-6 | ||
| Merck USA index | 14, 4719 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36/37-22 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves. Do not breathe dust. |
||
| R Phrase |
R: 22-36/37/38-42/43 Harmful if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by inhalation and skin contact. |
||
