372770
HBDDE
2,2′,3,3′,4,4′-Hexahydroxy-1,1′-biphenyl-6,6′-dimethanol Dimethyl Ether
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
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A cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKCα (IC50 = 43 µM) and PKCγ (IC50 = 50 µM) over PKCδ, βI, and βII isozymes in in vitro assays. Reported to induce apoptosis in rodent cerebellar granule neurons.
| Product information | |||
|---|---|---|---|
| Form | Orange solid | ||
| Primary Target | PKCα | ||
| Primary Target IC50 | 43 µM | ||
| Secondary target | PKCγ (IC50 = 50 µM) | ||
| Molar mass | 338.3 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Cell permeable | Yes | ||
| Purity | ≥95% by TLC | ||
| Solubility | DMSO, EtOH, or warm H2O | ||
| Chemical formula | C16H18O8 | ||
| CAS number | 154675-18-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
