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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Fax: +49 6151 72 2000
15 Februar 2012
wird geladen
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC50 = 4 nM for rat brain PKC). Inhibits protein kinase A (IC50 = 510 nM), protein kinase G (IC50 = 4.8 µM), and myosin light chain kinase (IC50 = 120 nM) at much higher concentrations.
| Produktinformationen | |||
|---|---|---|---|
| Form | Amber solid | ||
| Primary Target | PKC | ||
| Primary Target IC50 | 4 nM | ||
| Secondary target | MLCK (IC50 = 120 nM), PKA (IC50 = 150 nM) | ||
| Protect from Light | Ja | ||
| Purity | ≥97% by HPLC | ||
| Chemische Formel | C27H26N4O4 · HCl | ||
| CAS-Nummer | 287935-76-6 | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
| Lagerkategorie | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
