346002
Glucagon Receptor Antagonist, Control
N-(3-Cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl)-4-bromobenzamide, hGCGR Antagonist, Control
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
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This product has been discontinued.
We apologize for the inconvenience, but we do not currently have an alternative product. We currently carry only the active form of this product, Glucagon Receptor Antagonist I (Cat. No. 346001)
A cell-permeable thienyl-amide compound that serves as an inactive control for Glucagon Receptor Antagonist (Cat. No. 346001). Displays weak affinity to hGCGR and is ineffective in preventing glucagon binding (20% inhibition at 10 µM in membranes prepared from CHO-hGCGR) and glucagon-, forskolin-, and GIP-induced cAMP production (10% inhibition in CHO-hGCGR cells). Only minimally suppresses glucagon-induced glycogenolysis in human primary hepatocytes.
| Product information | |||
|---|---|---|---|
| Form | Light yellow solid | ||
| Molar mass | 431.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C21H23BrN2OS | ||
| CAS number | 362482-00-6 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling |
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