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Aminoglycoside related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial
neor/
kanr genes. The product of these genes, aminoglycoside 3′-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Introduction of either of these genes into cells can confer resistance to G418, which enables cells to grow in media containing G418.
Also available as a sterile-filtered solution (Cat. No.
345812).
| Accesorios paraG 418 Sulfate, Cell Culture Tested |
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Información sobre producto
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Form
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White powder
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Biological activity
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Assay: ≥730 µg/mg
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Purity
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≥98% by TLC
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Contaminants
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Ammonia: ≤1.0%; heavy metals: ≤100 ppm
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Fórmula químico
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C20H40N4O10 · 2H2SO4
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RTECS
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CB9378500
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Número CAS
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108321-42-2
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Almacenar y enviar información
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Categoría de alamacenamiento
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+15°C to +30°C
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Ship
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Ambient Temperature Only
Standard Handling
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