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Merck KGaA
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15 February 2012
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Aminoglycoside related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial neor/kanr genes. The product of these genes, aminoglycoside 3′-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Introduction of either of these genes into cells can confer resistance to G418, which enables cells to grow in media containing G418.
Also available as a sterile-filtered solution (Cat. No. 345812).
| Alternatives | |
|---|---|
| 345812 | G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested |
| Alternative products for G 418 Sulfate, Cell Culture Tested | |
| 345812 | G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested |
| Accessories forG 418 Sulfate, Cell Culture Tested |
| Product information | |||
|---|---|---|---|
| Form | White powder | ||
| Molar mass | 692.7 | ||
| Biological activity | Assay: ≥730 µg/mg | ||
| Purity | ≥98% by TLC | ||
| Contaminants | Ammonia: ≤1.0%; heavy metals: ≤100 ppm | ||
| pH value | 4.0 -6.0 | ||
| Solubility | H2O | ||
| Chemical formula | C20H40N4O10 · 2H2SO4 | ||
| RTECS | CB9378500 | ||
| CAS number | 108321-42-2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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