329600
Erastin
2-(1-(4-(2-(4-Chlorophenoxy)acetyl)-piperazin-1-yl)-ethyl)-3-(2-ethoxyphenyl)-3H-quinazolin-4-one
Para preguntas en general por favor contacte a nuestro Servicio de Atención al Cliente:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Teléfono: +49 6151 72-0
Fax: +49 6151 72 2000
14 febrero 2012
cargando
A cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality. Shown to bind mitochondrial volatage-dependent anion channels (VDAC) and alter its gating; rapidly induce an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling (EC50 = 6.0 µM in BJ-TERT/LT/ST/RASV12 cells).
| Información sobre producto | |||
|---|---|---|---|
| Form | White solid | ||
| Protect from Light | Si | ||
| Packaged under inert gas | Si | ||
| Purity | ≥98% by HPLC | ||
| Fórmula químico | C30H31ClN4O4 | ||
| Número CAS | 571203-78-6 | ||
| Almacenar y enviar información | |||
|---|---|---|---|
| Categoría de alamacenamiento | -20°C | ||
| Ship |
Blue Ice Only
Standard Handling |
||
