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15 February 2012
loading
Native, human des-Arg C3 complement component. Single chain, 76 amino acid peptide. Once the C3a peptide has been produced in human plasma or serum, it is rapidly converted to C3a des-Arg upon removal of the C-terminal arginine by endogenous serum carboxypeptidase N. This enzymatic process is considered to be a major mechanism for controlling C3a function in vivo because C3a des-Arg has <1% of the biological activity expressed by the C3a peptide. Therefore, C3a des-Arg can serve as a negative control molecule in experiments involved with the biological activities of the intact C3a anaphylatoxin peptide.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In PBS, pH 7.2. | ||
| Preservative | ≤0.1% sodium azide | ||
| Molar mass | 9000 | ||
| Avoid freeze/thaw | Yes | ||
| Biological activity | Ileum contraction assay: negative | ||
| Purity | ≥90% by SDS-PAGE | ||
| Source | Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
