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Merck KGaA
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64293 Darmstadt
Germany
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Fax: +49 6151 72 2000
15 February 2012
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Water-soluble reagent useful for the reduction of native disulfide bonds in proteins. Considered to be a superior reducing agent to DTT. Shown to reduce accessible disulfide bonds in immunoglobulin and trypsinogen under non-denaturing conditions 5 to 7 times faster than DTT at pH 7. The relatively less accessible disulfide bond in α-chymotrypsinogen A was reduced 2.3 times faster at with BMS than with DTT at pH 7.0.
| Product information | |||
|---|---|---|---|
| Form | White crystalline solid | ||
| Molar mass | 186.3 | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥99% by titration | ||
| PKA | 7.9 and 9.0 | ||
| Solubility | DMSO, EtOH, H2O, or MeOH | ||
| Chemical formula | C4H10O2S3 | ||
| CAS number | 145626-87-5 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
