203292
Bisindolylmaleimide II
2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
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A potent, cell permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC50 = 13 nM). May inhibit protein kinase A at much higher concentrations (IC50 = 2 µM).
| Product information | |||
|---|---|---|---|
| Form | Orange solid | ||
| Primary Target | PKC | ||
| Primary Target IC50 | 13 nM | ||
| Secondary target | PKA (IC50 = 2 mM) | ||
| Molar mass | 438.5 | ||
| Cell permeable | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C27H26N4O2 | ||
| CAS number | 137592-45-1 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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