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Merck KGaA
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64293 Darmstadt
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Phone: +49 6151 72-0
Fax: +49 6151 72 2000
15 February 2012
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Specific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications.
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| Product information | |||
|---|---|---|---|
| Form | White to off-white solid | ||
| Primary Target | chymotrypsin | ||
| Secondary target | kallikrein, plasmin, trypsin | ||
| Molar mass | 239.5 | ||
| Protect from Moisture | Yes | ||
| Purity | >97% by HPLC | ||
| Solubility | H2O | ||
| Chemical formula | C8H10FNO2S · HCl | ||
| CAS number | 30827-99-7 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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| Data | |||
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