For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
14 February 2012
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Methylation of biological molecules and proteins plays an important role in signal transduction, biosynthesis, protein repair, gene silencing and chromatin regulation. The SAM Methyltransferase Assay is a continuous enzyme coupled assay that can monitor SAM dependent methyltransferases without the use of radioactive labels or endpoint measurements.
| Product information | |||
|---|---|---|---|
| Format | 96-well plate | ||
| Form | 100 Tests | ||
| Detection method | Colorimetric | ||
| Assay range | 0.013-0.133 µmol/min/ml | ||
| Kit contains | SAM Methyltransferase Assay Buffer, Adenosylhomocysteine, Methyltransferase Enzyme Mix, SAM Methyltransferase Assay Buffer additive, SAM Colorimetric Mix | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Irritant |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
||
| R Phrase |
R: 36/37/38 Irritating to eyes, respiratory system and skin. |
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| Data | |||
|---|---|---|---|
    Left Panel: Assay using the Adenosylhomocysteine positive control. Right Panel: Human lysine specific histone methyltransferase SET7/9 was measured as outlined in the Detailed Protocol using 20 µM TAF-10 as the acceptor substrate. 
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