A cell-permeable, amphiphilic amino-steroid that alters intracellular membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol, presumably via its inhibitory effect on 2,3-oxidosqualene-lanosterol cyclase activity. Also reported to inhibit the activity of Δ8-sterol isomerase.
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Product information
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Form
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Lyophilized white solid
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Primary Target
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activity of Δ8-sterol isomerase
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Molar mass
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424.1
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Hygrocopic
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Yes
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Packaged under inert gas
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Yes
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Cell permeable
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Yes
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Purity
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≥95% by TLC
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Solubility
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H2O
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Chemical formula
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C25H41NO2 • HCl
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CAS number
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3039-71-2
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Store and ship information
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Storage
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+2°C to +8°C
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Ship
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Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling
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