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580551  Tautomycin, Streptomyces spiroverticillatus

Mixture of two isomers. Potent inhibitor of protein phosphatases. Inhibits protein phosphatase 1 (IC50 = 1 nM), protein phosphatase 2A (IC50 = 10 nM), and smooth muscle endogenous phosphatase (IC50 = 6 nM). Higher concentrations are needed to inhibit protein phosphatase 2B. Does not inhibit protein phosphatase 2C.
Product number Size Quantity Price
580551-50UG  50 μg  price on request 
Product information
Form Lyophilized thin film
Primary Target PP1
Primary Target IC50 1 nM
Secondary target 2A (IC50 = 10 nM), and smooth muscle endogenous phosphatase (IC50 = 6 nM)
Molar mass 767.0
Protect from Light Yes
Protect from Moisture Yes
Purity ≥97% by HPLC
Solubility CHCl3, EtOH, or MeOH
Chemical formula C41H66O13
RTECS WX1000000
CAS number 109946-35-2
Store and ship information

Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Storage -20°C
Ship Ambient Temperature Only
Highly Toxic
Safety information
S Phrase S: 22-36/37/39-45

Do not breathe dust.

In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
R Phrase R: 26/27/28

Tautomycin, <i>Streptomyces spiroverticillatus</i>, molecular structure

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