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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
14 February 2012
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Mixture of two isomers. Potent inhibitor of protein phosphatases. Inhibits protein phosphatase 1 (IC50 = 1 nM), protein phosphatase 2A (IC50 = 10 nM), and smooth muscle endogenous phosphatase (IC50 = 6 nM). Higher concentrations are needed to inhibit protein phosphatase 2B. Does not inhibit protein phosphatase 2C.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized thin film | ||
| Primary Target | PP1 | ||
| Primary Target IC50 | 1 nM | ||
| Secondary target | 2A (IC50 = 10 nM), and smooth muscle endogenous phosphatase (IC50 = 6 nM) | ||
| Molar mass | 767.0 | ||
| Protect from Light | Yes | ||
| Protect from Moisture | Yes | ||
| Purity | ≥97% by HPLC | ||
| Solubility | CHCl3, EtOH, or MeOH | ||
| Chemical formula | C41H66O13 | ||
| RTECS | WX1000000 | ||
| CAS number | 109946-35-2 | ||
| Store and ship information | |||
|---|---|---|---|
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Highly Toxic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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| R Phrase |
R: 26/27/28 Very toxic by inhalation, in contact with skin and if swallowed. |
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