Recombinant, human PP2AI I1 fused to GST and expressed in E. coli. Acts as a potent, heat-stable, specific, and non-competitive inhibitor of PP2A (Ki = 30 nM with myelin basic protein, histone H1, or phosphorylase as substrates for PP2A). Does not inhibit PP1, PP2B, or PP2C, or pyruvate dehydrogenase phosphatase.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 50 mM Tris-HCl, 14 mM β-mercaptoethanol, 1 mM benzamidine, 1 mM EDTA, 100 µM PMSF, 10% glycerol, 0.1% BRIJ®-35 detergent, pH 7.4. | ||
| Primary Target | PP2A | ||
| Primary Target Ki | 30 nM | ||
| Molar mass | 58000 | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥90% by SDS-PAGE | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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