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506136  p53, MDM-2 Binding Domain, N-Terminal 17-26, Cell-Permeable

PNC-28, ETFSDLWKLL-KKWKMRRNQFWVKVQRG

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14 February 2012

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Product number Size Quantity Price
506136-500UG  500 μg 
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Prices are subject to change without notice.
A decapeptide derived from the N-terminal MDM-2 binding domain of p53, residues 17 - 26, and linked to the Antennapedia leader sequence at the C-terminal. Exerts anti-proliferative activities. Directly binds to MDM-2 and induces non-apoptotic cell-death (IC50 = 40 µg/ml in TUC-3 cells) that is independent of p53 activation. Reported to have no effect on the growth of normal cells.
Product information
Peptide Sequence H-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly-OH
Form Lyophilized
Formulation Supplied as a trifluoacetate salt.
Molar mass 3509.2
Protect from Light Yes
Hygrocopic Yes
Packaged under inert gas Yes
Purity ≥95% by HPLC
Solubility H2O
Chemical formula C164H255N47O37S
Store and ship information
Storage -20°C
Ship Blue Ice Only
Standard Handling

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