Naturally-occurring ion channel-forming pentadecapeptide. The association of two gA peptides causes the formation of a monovalent cation-selective ion channel. Causes K+/H+ exchange in mitochondria in a non-voltage dependent manner. Causes red blood cell lysis at 0.5-1.0 µg/ml.
| Accessories for Gramicidin A, High Purity, Bacillus brevis |
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Product information
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Peptide Sequence
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HCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH
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Form
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White to off-white solid
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Molar mass
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1882.3
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Purity
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≥95% by HPLC
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Contaminants
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gB and gC isomers: <1% by HPLC
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Solubility
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DMSO
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Chemical formula
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C99H140N20O17
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RTECS
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MD8230000
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CAS number
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11029-61-1
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Merck USA index
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14, 4532
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Store and ship information
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Storage
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-20°C
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Ship
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Ambient Temperature Only
Harmful
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Safety information
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S Phrase
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S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.
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R Phrase
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R: 20/21/22-36/37/38
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