Potent cell-permeable anticancer agent whose potential target site may be mitochondrial cytochrome c oxidase. Has been shown to inhibit RNA and DNA synthesis. Inhibits eukaryotic topoisomerases I and II. Induces DNA single-strand breaks. Also induces apoptosis in HeLa S3 tumor cells.
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Product information
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Form
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Red crystalline solid
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Primary Target
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DNA synthesis, RNA synthesis
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Molar mass
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564.0
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Hygrocopic
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Yes
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Cell permeable
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Yes
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Purity
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Potency: ≥840 µg/mg
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Solubility
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H2O
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Chemical formula
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C27H29NO10 · HCl
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RTECS
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HB7878000
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CAS number
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23541-50-6
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Merck USA index
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14, 2832
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Store and ship information
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Storage
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+15°C to +30°C
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Ship
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Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic
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Safety information
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R Phrase
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R: 22;
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