Recombinant, rat DARPP-32 expressed in E. coli and phosphorylated on Thr34 by cAMP-dependent protein kinase (PKA). Acts as a potent inhibitor of protein phosphatase-1 (PP1; IC50 = 1 nM). It is dephosphorylated and inactivated by PP2A and PP2B.
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Product information
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Form
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White lyophilized solid
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Primary Target
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PP1
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Primary Target IC50
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1 nM
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Molar mass
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32000
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Hygrocopic
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Yes
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Purity
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≥95% by SDS-PAGE
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Solubility
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50 mM Tris-HCl buffer, pH 7.0
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Store and ship information
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Storage
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-20°C
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Ship
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Ambient Temperature Only
Standard Handling
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