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Merck KGaA
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14 February 2012
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An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µM-1 S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/- mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | Abz-His-Pro-Gly~Gly-Pro-Gln-EDDnp | ||
| Form | Bright yellow solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Molar mass | 918.4 | ||
| Protect from Light | Yes | ||
| Protect from Moisture | Yes | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Excitation max. | 320 nM | ||
| Emission max. | 420 nM | ||
| Solubility | DMSO | ||
| Chemical formula | C40H50N14O12 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Blue Ice Only
Standard Handling |
||
