203291
Bisindolylmaleimide I, Hydrochloride
2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide, HCl
An enhanced water-soluble form of Bisindolylmaleimide I (Cat. No. 203290). A reversible and ATP-competitive inhibitor of protein kinase C (Ki = 10 nM). May inhibit protein kinase A at much higher concentrations (Ki = 2 µM).
| Product information | |||
|---|---|---|---|
| Form | Orange-red solid | ||
| Primary Target | PKC | ||
| Primary Target Ki | 10 nM | ||
| Secondary target | PKA (Ki = 2 mM) | ||
| Molar mass | 448.9 | ||
| Cell permeable | Yes | ||
| Reversible | Yes | ||
| ATP Competitive | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO or H2O | ||
| Chemical formula | C25H24N4O2 · HCl | ||
| CAS number | 176504-36-2 | ||
| Declaration | Sold under license of U.S. Patent 5,380,746. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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