116819
Adenosine 3′,5′-cyclic Monophosphorothioate, 8-Chloro-, Rp-Isomer, Sodium Salt
Rp-8-Cl-cAMPS, Na
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14 February 2012
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A cell-permeable, metabolically-stable analog of cAMP that acts as a competitive inhibitor of protein kinase A. Lipophilic analog of the cAMP antagonist Rp-cAMPS (Cat. No. 116814). Preferentially inhibits type I PKA (IC50 = ~50 µM).
Note: 5 µmol = 2 mg.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Primary Target | PKA 1 | ||
| Primary Target IC50 | 50 µM | ||
| Secondary target | Cholera toxin (IC50=300 µM) | ||
| Molar mass | 401.7 | ||
| Hygrocopic | Yes | ||
| Cell permeable | Yes | ||
| ATP Competitive | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | H2O | ||
| Chemical formula | C10H10ClN5O5PS · Na | ||
| CAS number | 142754-27-6 | ||
| Declaration | Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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