RonaCare® MAP- Biotechnologically Derived Magnesium Ascorbyl Phosphate
L-ascorbic acid, one of the best-known antioxidants, is also involved in many biological processes such as collagen synthesis, intestinal absorption of iron and metabolism of some amino acids. Unfortunately, however, it is unstable in aqueous solutions.Merck`s RonaCare® MAP, the magnesium salt of the 2-phosphate ester of ascorbic acid, provides an active form of vitamin C in the dermis. It is derived enzymatically by the regiospecific phosphorylation of vitamin C. As can be seen in the diagram below, RonaCare® MAP provides long term stable vitamin C.
Stability in Aqueous Solution
It retains over 95 % of its potency at 40 °C in aqueous solutions without any pH adjustment.
Tyrosinase Inhibition
RonaCare® MAP is capable of suppressing the pigmentation of skin by inhibiting tyrosinase activity. It is very effective in whitening dark skins, or areas of dark skin. The following chart shows the inhibitory effect of RonaCare® MAP on tyrosinase.
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