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RonaCare® Information

RonaCare® ASC III® - A Collagen III Amplifier System

Key Properties and Claims

RonaCare® ASC III® is an effective amplifier of collagen III. It selectively increases collagen III production by enhancing the fibroblast activity via modulating cytokine production. The significant increase in pro-collagen III (the juvenile collagen) accompanied by a pronounced increase of the epidermal layer thickness results in an improvement in dermal/epidermal junction area and reformation of collagen fibers in the dermis.

Skin care products containing RonaCare® ASC III® can, therefore, repair the natural collagen support layer that lies just beneath the skin, resulting in increased skin elasticity and smoothness and reduction of facial lines and wrinkles.

ChemPortals PTP - Cosmetics - RonaCare ASCIIIvor.jpg

Chemportals PTP - Cosmetics - RonaCare ASCIIInach.jpg

Study of human skin  
a) before treatment b) after three weeks treatment with a gel
containing 5 % RonaCare® ASC III®

Efficacy Studies

In vitro studies:In-vivo studies:
  • Selective increase of collagen III in human fibroblasts
  • Cell proliferation study in fibroblasts: no proliferation after application of RonaCare® ASCIII®, induction of fibroblast activity
  • No collagenase stimulation
  • Cutometer study for skin elasticity: 35 % increase
  • Study of facial skin after biopsy: improvement in dermal/epidermal junction
  • Amplifier of collagen III
  • Increase in epidermal layer thickness
  • Improvement in dermal/epidermal junction area
  • Reformation of collagen fibers
  • Increased skin elasticity
  • Reduction of wrinkles

You will find all relevant documents and certificates concerning your chosen product under the heading 'Related Documents'. Brochures are available on request.

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© Merck KGaA, Darmstadt, Germany, 2012

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