616453
TGF-β RI Kinase Inhibitor III
2-(5-Benzo[1,3]dioxol-4-yl-2-tert-butyl-1H-imidazol-4-yl)-6-methylpyridine, HCl, Transforming Growth Factor-β Type I Receptor Kinase Inhibitor III, ALK5 Inhibitor III
Para informações, por favor, contate o nosso Serviço de Atendimento ao Cliente
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefone: +49 6151 72-0
Fax: +49 6151 72 2000
11 Fevereiro 2012
carregando
| Nº de produto | Tamanho |
|---|---|
| 616453-2MG | 2 mg |
A cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of activin receptor-like kinase 4 (IC50 = 129 nM), 5 ( IC50 = 47 nM), and 7. It inhibits p38 MAPKα only at much higher concentrations (IC50 = 10.6 µM) and has little effect against ALK1/2/3/6 as well as a panel of 26 other kinases.
| Informações sobre o produto | |||
|---|---|---|---|
| Form | Light yellow solid | ||
| Protect from Light | Sim | ||
| Hygrocopic | Sim | ||
| Packaged under inert gas | Sim | ||
| Purity | ≥97% by HPLC | ||
| Fórmula Química | C20H21N3O2 • HCl | ||
| Número CAS | 356559-13-2 | ||
| Informação de estoque e transporte | |||
|---|---|---|---|
| Armazenagem | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Irritant |
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