236012
COX-2 Inhibitor II
SC-791, 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefone: +49 6151 72-0
Fax: +49 6151 72 2000
13 Fevereiro 2012
carregando
| Nº de produto | Tamanho |
|---|---|
| 236012-5MG | 5 mg |
A cell-permeable isoxazolyl-benzenesulfonamide compound that acts as a potent and highly selective inhibitor of COX-2 both in vitro (IC50 = 4 nM for hCOX-2 vs. 114 µM for hCOX-1) and in vivo. Has been used extensively in various animal models to study the role of COX-2 in wound healing process.
| Informações sobre o produto | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Primary Target | hCOX-2 | ||
| Primary Target IC50 | 4 nM | ||
| Secondary target | hCOX-1 (IC50 = 114 µM) | ||
| Protect from Light | Sim | ||
| Packaged under inert gas | Sim | ||
| Cell permeable | Sim | ||
| Purity | ≥98% by HPLC | ||
| Fórmula Química | C16H12F2N2O3S | ||
| Número CAS | 181696-33-3 | ||
| Informação de estoque e transporte | |||
|---|---|---|---|
| Armazenagem | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
