236005
COX-1 Inhibitor, FR122047
FR 122047, 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride, 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride
Para informações, por favor, contate o nosso Serviço de Atendimento ao Cliente
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefone: +49 6151 72-0
Fax: +49 6151 72 2000
13 Fevereiro 2012
carregando
| Nº de produto | Tamanho |
|---|---|
| 236005-5MG | 5 mg |
A cell-permeable trisubstituted thiazole compound that acts as a potent and selective inhibitor of COX-1 (IC50 = 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively). Displays ~2,300 fold greater selectivity towards inhibition of COX-1 over COX-2. Reported to be orally active and display analgesic, anti-platelet and anti-inflammatory properties.
| Informações sobre o produto | |||
|---|---|---|---|
| Form | Pale yellow solid | ||
| Primary Target | COX-1, COX-2 | ||
| Primary Target IC50 | 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively | ||
| Protect from Light | Sim | ||
| Hygrocopic | Sim | ||
| Packaged under inert gas | Sim | ||
| Cell permeable | Sim | ||
| Purity | ≥98% by HPLC | ||
| Fórmula Química | C23H25N3O3S • HCl | ||
| Número CAS | 130717-51-0 | ||
| Informação de estoque e transporte | |||
|---|---|---|---|
| Armazenagem | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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